Biological properties of Shigella flexneri 2A toxin and its serological relationship to Shigella dysenteriae 1 toxin-Reference-Cited by-同舟云学术

Biological properties of Shigella flexneri 2A toxin and its serological relationship to Shigella dysenteriae 1 toxin

Published:1977-03 Issue:3 Volume:15 Page:796-798
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

O'Brien A D,Thompson M R,Gemski P,Doctor B P,Formal S B

Abstract

A toxin extracted from heat-inactivated, alkaline-treated Shigella flexneri 2a showed biological properties similar to those of Shigella dysenteria 1 toxin. The S, flexneri 2a toxin was lethal to mice, enterotoxic for ileal loops of rabbits, and cytotoxic for HeLa cells. A serological relationship between S. flexneri 2a and S. dysenteriae 1 toxin was shown with cross neutralization tests.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.15.3.796-798.1977

Reference14 articles.

1. Use of ligated segments of rabbit small intestine in experimental shigellosis;Arm H. G.;J. Bacteriol.,1965

2. Ueber losliche, durch aseptische Autolyse erhaltene Giftstoffe von Ruhr-und Typhus-bazillen;Conradi H.;Dtsch. Med. Wochenschr.,1903

3. Preparation and properties of Shiga toxin and toxoid;Dubos R. J.;J. Exp. Med.,1946

4. Fluorescent-antibody and histological studies of vaccinated control monkeys challenged with Shigella flexneri;Formal S. B.;J. Bacteriol.,1966

5. Studies with Vibrio cholerae in the ligated loop of the rabbit intestine;Formal S. B.;Br. J. Exp. Pathol.,1961

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