Forty Years of Oxalobacter formigenes, a Gutsy Oxalate-Degrading Specialist-Reference-Cited by-同舟云学术

Forty Years of Oxalobacter formigenes, a Gutsy Oxalate-Degrading Specialist

Published:2021-08-26 Issue:18 Volume:87 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Daniel Steven L.¹^ORCID,Moradi Luke²,Paiste Henry²,Wood Kyle D.³,Assimos Dean G.³,Holmes Ross P.³,Nazzal Lama⁴,Hatch Marguerite⁵,Knight John³

Affiliation:

1. Department of Biological Sciences, Eastern Illinois University, Charleston, Illinois, USA

2. School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA

3. Department of Urology, University of Alabama at Birmingham, Birmingham, Alabama, USA

4. Department of Medicine, NYU Grossman School of Medicine, New York, New York, USA

5. Department of Pathology, Immunology & Laboratory Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA

Abstract

Oxalobacter formigenes , a unique anaerobic bacterium that relies solely on oxalate for growth, is a key oxalate-degrading bacterium in the mammalian intestinal tract. Degradation of oxalate in the gut by O. formigenes plays a critical role in preventing renal toxicity in animals that feed on oxalate-rich plants.

Funder

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.00544-21

Reference116 articles.

1. The Destruction of Oxalates by the Rumen Contents of Cows

2. Calcium assimilation in ruminants on oxalate-rich diet

3. Hodgkinson A. 1977. Oxalic acid in biology and medicine. Academic Press, New York, NY.