Multiple Alleles of Treponema pallidum Repeat Gene D in Treponema pallidum Isolates

Author:

Centurion-Lara Arturo1,Sun Eileen S.1,Barrett Lynn K.1,Castro Christa1,Lukehart Sheila A.1,Van Voorhis Wesley C.1

Affiliation:

1. Departments of Medicine and Pathobiology, University of Washington, Seattle, Washington 98195-7185

Abstract

ABSTRACT Two new tprD alleles have been identified in Treponema pallidum : tprD2 is found in 7 of 12 T. pallidum subsp. pallidum isolates and 7 of 8 non- pallidum isolates, and tprD3 is found in one T. pallidum subsp. pertenue isolate. Antibodies against TprD2 are found in persons with syphilis, demonstrating that tprD2 is expressed during infection.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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