Cetylpyridinium Chloride: Mechanism of Action, Antimicrobial Efficacy in Biofilms, and Potential Risks of Resistance

Author:

Mao Xiaojun1,Auer David L.1,Buchalla Wolfgang1,Hiller Karl-Anton1,Maisch Tim2,Hellwig Elmar3,Al-Ahmad Ali3,Cieplik Fabian1

Affiliation:

1. Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany

2. Department of Dermatology, University Hospital Regensburg, Regensburg, Germany

3. Department of Operative Dentistry and Periodontology, Center for Dental Medicine, University of Freiburg, Freiburg im Breisgau, Germany

Abstract

Antimicrobial resistance is a serious issue for public health care all over the world. While resistance toward antibiotics has attracted strong interest among researchers and the general public over the last 2 decades, the directly related problem of resistance toward antiseptics and biocides has been somewhat left untended. In the field of dentistry, antiseptics are routinely used in professional care, but they are also included in lots of oral care products such as mouthwashes or dentifrices, which are easily available for consumers over-the-counter.

Funder

Deutsche Gesellschaft für Präventivzahnmedizin

Affiliated Stomatology Hospital of Tongji University

Deutsche Forschungsgemeinschaft

Universitätsklinikum Regensburg

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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