Rapid Increase in Carbapenemase-Producing Enterobacteriaceae in Retail Meat Driven by the Spread of the bla NDM-5 -Carrying IncX3 Plasmid in China from 2016 to 2018-Reference-Cited by-同舟云学术

Rapid Increase in Carbapenemase-Producing Enterobacteriaceae in Retail Meat Driven by the Spread of the bla NDM-5 -Carrying IncX3 Plasmid in China from 2016 to 2018

Published:2019-08 Issue:8 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Zhang Qianhui¹²,Lv Luchao¹²,Huang Xiuyu¹²,Huang Ying¹²,Zhuang Zilin¹²,Lu Jiaxun¹²,Liu Enyu¹²,Wan Miao¹²,Xun Haoliang¹²,Zhang Zhiwei¹²,Huang Jin¹²,Song Qianhua¹²,Zhuo Chao³,Liu Jian-Hua¹²

Affiliation:

1. College of Veterinary Medicine, National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, Key Laboratory of Zoonosis of Ministry of Agricultural and Rural Affairs, South China Agricultural University, Guangzhou, China

2. Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, China

3. State Key Laboratory of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China

Abstract

The presence and molecular characteristics of carbapenemase-producing Enterobacteriaceae (CPE) among meat products in China were investigated. A total of 110 carbapenem-resistant Enterobacteriaceae (CRE) isolates, including 94 Escherichia coli and 10 Klebsiella pneumoniae isolates, were identified from 105 of 794 (13.2%) samples. The positive rates markedly increased from 2016 (9.4%) to 2018 (22.2%). Only bla NDM genes were detected; 79.1% of bla NDM genes were carried by IncX3 plasmids.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00573-19

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