Lack of effective bactericidal activity of new quinolones against Brucella spp-Reference-Cited by-同舟云学术

Lack of effective bactericidal activity of new quinolones against Brucella spp

Published:1991-04 Issue:4 Volume:35 Page:756-759
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

García-Rodriguez J A¹,García Sánchez J E¹,Trujillano I¹

Affiliation:

1. Department of Microbiology, Facultad de Medicina, Hospital Clinico Universitario, Salamanca, Spain.

Abstract

The in vitro activities of six fluoroquinolones against 43 Brucella spp. were compared by testing three different inocula at two medium pH values. The influence of the test conditions was moderate. The activities of all quinolones were lower at pH 5 and with a high inoculum size. Results indicate the lack of effective bactericidal activity of quinolones against most strains of Brucella spp., particularly B. abortus.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.35.4.756

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