Detection of Clostridium difficile Toxin: Comparison of Enzyme Immunoassay Results with Results Obtained by Cytotoxicity Assay-Reference-Cited by-同舟云学术

Detection of Clostridium difficile Toxin: Comparison of Enzyme Immunoassay Results with Results Obtained by Cytotoxicity Assay

Published:2007-08 Issue:8 Volume:45 Page:2737-2739
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Musher Daniel M.¹²,Manhas Atisha¹²,Jain Pranav¹,Nuila Franziska¹,Waqar Amna¹,Logan Nancy¹²,Marino Bernard¹²,Graviss Edward A.¹³

Affiliation:

1. Medical Service (Infectious Disease Section), Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas

2. Departments of Medicine and Molecular Virology and Microbiology, Baylor College of Medicine

3. Department of Pathology, Baylor College of Medicine, Houston, Texas

Abstract

ABSTRACT Several kinds of laboratory techniques are available to detect Clostridium difficile toxin in fecal samples. Because questions have been raised about the reliability of immunoassays compared to the accepted standard, cytotoxicity assay, we studied three enzyme immunoassays (EIAs) and one rapid EIA, which demonstrated relatively good sensitivities and specificities compared to cytotoxicity assay.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00686-07

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