Neutralizing Viruses in Suspensions by Copper Oxide-Based Filters

Author:

Borkow Gadi12,Sidwell Robert W.3,Smee Donald F.3,Barnard Dale L.3,Morrey John D.3,Lara-Villegas Humberto H.1,Shemer-Avni Yonat4,Gabbay Jeffrey2

Affiliation:

1. Ruth Ben-Ari Institute of Clinical Immunology, Kaplan Medical Center, Rehovot 76100, Israel

2. Cupron, Inc., POB 10973, Greensboro, NC 27404

3. Institute for Antiviral Research, Utah State University, Logan, Utah 84322-5600

4. Department of Virology, Faculty of Health Sciences, Soroka Academic Medical Center, Beer-Sheva 84105, Israel

Abstract

ABSTRACT We report the capacity of copper oxide-containing filters to reduce infectious titers of a panel of viruses spiked into culture media. Enveloped, nonenveloped, RNA, and DNA viruses were affected, suggesting the possibility of using copper oxide-containing devices to deactivate a wide spectrum of infectious viruses found in filterable suspensions.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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