Construction and characterization of an isogenic urease-negative mutant of Helicobacter mustelae-Reference-Cited by-同舟云学术

Construction and characterization of an isogenic urease-negative mutant of Helicobacter mustelae

Published:1995-09 Issue:9 Volume:63 Page:3718-3721
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Solnick J V¹,Josenhans C¹,Suerbaum S¹,Tompkins L S¹,Labigne A¹

Affiliation:

1. Division of Infectious Diseases, University of California, Davis, School of Medicine, USA.

Abstract

Helicobacter mustelae infects the ferret stomach and provides an opportunity to study pathogenic determinants of a Helicobacter species in its natural host. We constructed an isogenic urease-negative mutant of H. mustelae which produced no detectable urease and showed a reduced acid tolerance. This mutant provides an opportunity to further evaluate the role of urease in the pathogenesis of Helicobacter infection.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.63.9.3718-3721.1995

Reference30 articles.

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