Bacteriostatic, Fungistatic, and Algistatic Activity of Fatty Nitrogen Compounds

Author:

Hueck Hendrik J.12,Adema Dorothea M. M.12,Wiegmann John R.12

Affiliation:

1. Central Laboratory TNO, Delft, The Netherlands

2. General Mills Incorporated Central Research, Minneapolis, Minnesota

Abstract

A total of 164 fatty nitrogen compounds, consisting of quaternary ammonium compounds, alkylamines, N -alkyl-1, 3-propylene diamines, substituted amino hydroxystearonitriles, substituted amino hydroxystearyl amines, and nitrogen-containing surfactants, were screened for bacteriostatic, fungistatic, and algistatic activity. The most active compounds were dodecylamine and dodecylamine acetate. A number of compounds were very active against gram-negative bacteria. Most of the surfactants were virtually nontoxic to all of the test organisms.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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