Chemoenzymatic Synthesis ofN-Acetyl-d-Neuraminic Acid fromN-Acetyl-d-Glucosamine by Using the Spore Surface-DisplayedN-Acetyl-d-Neuraminic Acid Aldolase-Reference-Cited by-同舟云学术

Chemoenzymatic Synthesis ofN-Acetyl-d-Neuraminic Acid fromN-Acetyl-d-Glucosamine by Using the Spore Surface-DisplayedN-Acetyl-d-Neuraminic Acid Aldolase

Published:2011-08-05 Issue:19 Volume:77 Page:7080-7083
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl. Environ. Microbiol.

Author:

Gao Chao,Xu Xiaoman,Zhang Xifeng,Che Bin,Ma Cuiqing,Qiu Jianhua,Tao Fei,Xu Ping

Abstract

ABSTRACTChemoenzymatic synthesis ofN-acetyl-d-neuraminic acid fromN-acetyl-d-glucosamine using the spore surface-displayedN-acetyl-d-neuraminic acid aldolase at a high concentration (53.9 g liter−1) was achieved in this study. Thus, displaying a target enzyme on the surface of spores might be an alternative for integration of biocatalytic conversion into chemical synthesis.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference24 articles.

1. Characterization of the chemoenzymatic synthesis of N-acetyl-d-neuraminic acid (Neu5Ac);Blayer;Biotechnol. Prog.,1996

2. Alkaline biocatalysis for the direct synthesis of N-acetyl-d-neuraminic acid (Neu5Ac) from N-acetyl-d-glucosamine (GlcNAc);Blayer;Biotechnol. Bioeng.,1999

3. Surface display of recombinant proteins on Bacillus thuringiensis spores;Du;Appl. Environ. Microbiol.,2005

4. Inhibition of Bacillus anthracis spore outgrowth by nisin;Gut;Antimicrob. Agents Chemother.,2008

5. Integration of biocatalytic conversions into chemical syntheses;Hailes;J. Chem. Technol. Biotechnol.,2007

Cited by 20 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Applications of Bacillus subtilis Protein Display for Medicine, Catalysis, Environmental Remediation, and Protein Engineering;Microorganisms;2024-01-03

2. Biocatalyzed Carbon–Carbon bond formation in enantioselective synthesis;Biocatalysis in Asymmetric Synthesis;2024

3. Current Status of Bacillus subtills Spore Surface Display System and Its Biotechnological Applications for Two Decades;KSBB Journal;2023-03-31

4. Cecal Metabolomic Fingerprint of Unscathed Rats: Does It Reflect the Good Response to a Provocative Decompression?;Frontiers in Physiology;2022-05-17

5. Advances in engineered Bacillus subtilis biofilms and spores, and their applications in bioremediation, biocatalysis, and biomaterials;Synthetic and Systems Biotechnology;2021-09