Frequency and Abundance of Alphaherpesvirus DNA in Human Thoracic Sympathetic Ganglia-Reference-Cited by-同舟云学术

Frequency and Abundance of Alphaherpesvirus DNA in Human Thoracic Sympathetic Ganglia

Published:2014-04-30 Issue:14 Volume:88 Page:8189-8192
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J. Virol.

Author:

Nagel Maria A.,Rempel April,Huntington Jonathon,Kim Forrest,Choe Alexander,Gilden Don

Abstract

Alphaherpesvirus reactivation from thoracic sympathetic ganglia (TSG) and transaxonal spread to target organs cause human visceral disease. Yet alphaherpesvirus latency in TSG has not been well characterized. In this study, quantitative PCR detected varicella-zoster virus (VZV), herpes simplex virus 1 (HSV-1), and HSV-2 DNA in 117 fresh TSG obtained postmortem from 15 subjects. VZV DNA was found in 76 (65%) ganglia from all subjects, HSV-1 DNA was found in 5 (4%) ganglia from 3 subjects, and no HSV-2 was found.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference25 articles.

1. Varicella-zoster virus DNA in human sensory ganglia;Gilden;Nature,1983

2. Localization of herpes simplex virus and varicella zoster virus DNA in human ganglia;Mahalingam;Ann. Neurol.,1992

3. Latent varicella-zoster virus is located predominantly in neurons in human trigeminal ganglia;Kennedy;Proc. Natl. Acad. Sci. U. S. A.,1998

4. Latent varicella-zoster virus in human dorsal root ganglia;Kennedy;Virology,1999

5. Quantitation of latent varicella-zoster virus and herpes simplex virus genomes in human trigeminal ganglia;Pevenstein;J. Virol.,1999

Cited by 30 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Reanalysis of single-cell RNA sequencing data does not support herpes simplex virus 1 latency in non-neuronal ganglionic cells in mice;Journal of Virology;2024-04-16

2. Analysis of the Risk Factors for Mechanical Allodynia in Herpetic Neuralgia: A Retrospective Cross-Sectional Study;Journal of Pain Research;2023-10

3. Reanalysis of single-cell RNA sequencing data does not support herpes simplex virus 1 latency in non-neuronal ganglionic cells in mice;2023-07-18

4. Zoster Vaccines;Plotkin's Vaccines;2023

5. A Guide to Preclinical Models of Zoster-Associated Pain and Postherpetic Neuralgia;Current Topics in Microbiology and Immunology;2021