The Population Genomics of Increased Virulence and Antibiotic Resistance in Human Commensal Escherichia coli over 30 Years in France-Reference-Cited by-同舟云学术

The Population Genomics of Increased Virulence and Antibiotic Resistance in Human Commensal Escherichia coli over 30 Years in France

Published:2022-08-09 Issue:15 Volume:88 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Marin Julie¹²^ORCID,Clermont Olivier¹²,Royer Guilhem¹²³⁴^ORCID,Mercier-Darty Mélanie⁵,Decousser Jean Winoc⁴⁶^ORCID,Tenaillon Olivier¹²^ORCID,Denamur Erick¹²⁷^ORCID,Blanquart François⁸^ORCID

Affiliation:

1. Université Sorbonne Paris Nord, INSERM, IAME, Bobigny, France

2. Université Paris Cité, INSERM, IAME, Paris, France

3. Génomique Métabolique, Genoscope, Institut François Jacob, CEA, CNRS, Université d’Evry, Université Paris-Saclay, Evry, France

4. AP-HP, Département de Prévention, Diagnostic et Traitement des Infections, Hôpital Henri Mondor, Créteil, France

5. AP-HP, Next Generation Sequencing Platform, University Hospital Henri Mondor, Créteil, France

6. EA 7380 Dynamyc Université Paris Est Creteil (UPEC), Ecole Nationale Vétérinaire d’Alfort (EnvA), Faculté de Médecine de Créteil, Créteil, France

7. AP-HP, Laboratoire de Génétique Moléculaire, Hôpital Bichat, Paris, France

8. Center for Interdisciplinary Research in Biology, CNRS, Collège de France, PSL Research University, Paris, France

Abstract

Escherichia coliis an opportunistic pathogen with the greatest burden of antibiotic resistance, one of the main causes of bacterial infections and an increasing concern in an aging population. Deciphering the evolutionary dynamics of virulence and antibiotic resistance in commensalE. coliis important to understand adaptation and anticipate future changes.

Funder

Assistance Publique - Hôpitaux de Paris

Centre National de la Recherche Scientifique

Commissariat à l'Énergie Atomique et aux Énergies Alternatives

Fondation pour la Recherche Médicale

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.00664-22

Reference78 articles.