Identification of Virulence Factors Involved in a Murine Model of Severe Achromobacter xylosoxidans Infection-Reference-Cited by-同舟云学术

Identification of Virulence Factors Involved in a Murine Model of Severe Achromobacter xylosoxidans Infection

Published:2023-07-18 Issue:7 Volume:91 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Wills Brandon M.¹,Garai Preeti¹,Riegert Molly O.¹,Sanchez Felix T.¹,Pickrum Adam M.²,Frank Dara W.¹^ORCID,Brockman Kenneth L.¹^ORCID

Affiliation:

1. Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA

2. Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA

Abstract

Achromobacter xylosoxidans (Ax) is an opportunistic pathogen and causative agent of numerous infections particularly in immunocompromised individuals with increasing prevalence in cystic fibrosis (CF). To date, investigations have focused on the clinical epidemiology and genomic comparisons of Ax isolates, yet little is known about disease pathology or the role that specific virulence factors play in tissue invasion or damage.

Funder

Cystic Fibrosis Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00037-23

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