Mucins Shed from the Laminated Layer in Cystic Echinococcosis Are Captured by Kupffer Cells via the Lectin Receptor Clec4F-Reference-Cited by-同舟云学术

Mucins Shed from the Laminated Layer in Cystic Echinococcosis Are Captured by Kupffer Cells via the Lectin Receptor Clec4F

Published:2023-06-15 Issue:6 Volume:91 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Barrios Anabella A.¹,Mouhape Camila¹,Schreiber Leonard²,Zhang Linyun²,Nell Juliane²,Suárez-Martins Mariana¹,Schlapp Geraldine³,Meikle María Noel³,Mulet Ana Paula³,Hsu Tsui-Ling⁴,Hsieh Shie-Liang⁴,Mourglia-Ettlin Gustavo¹,González Carlos⁵,Crispo Martina³^ORCID,Barth Thomas F. E.²,Casaravilla Cecilia¹,Jenkins Stephen J.⁶,Díaz Álvaro¹^ORCID

Affiliation:

1. Área Inmunología, Departamento de Biociencias (Facultad de Química) and Cátedra de Inmunología, Instituto de Química Biológica (Facultad de Ciencias), Universidad de la República, Montevideo, Uruguay

2. Institute of Pathology, University Ulm, Ulm, Germany

3. Unidad de Biotecnología en Animales de Laboratorio, Institut Pasteur de Montevideo, Montevideo, Uruguay

4. Genomics Research Center, Academia Sinica, Taipei, Taiwan

5. Independent Researcher, Montevideo, Uruguay

6. University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Abstract

Cystic echinococcosis is caused by the larval stages (hydatids) of cestode parasites belonging to the species cluster Echinococcus granulosus sensu lato , with E. granulosus sensu stricto being the main infecting species. Hydatids are bladderlike structures that attain large sizes within various internal organs of livestock ungulates and humans.

Funder

Agencia Nacional de Investigación e Innovación

Foreign and Commonwealth Office

UKRI | Medical Research Council

Comisión Sectorial de Investigación Científica (CSIC), Universidad de la República, Uruguay

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00031-23

Reference57 articles.