Role of the MexAB-OprM Efflux Pump of Pseudomonas aeruginosa in Tolerance to Tea Tree ( Melaleuca alternifolia ) Oil and Its Monoterpene Components Terpinen-4-ol, 1,8-Cineole, and α-Terpineol-Reference-Cited by-同舟云学术

Role of the MexAB-OprM Efflux Pump of Pseudomonas aeruginosa in Tolerance to Tea Tree ( Melaleuca alternifolia ) Oil and Its Monoterpene Components Terpinen-4-ol, 1,8-Cineole, and α-Terpineol

Published:2008-03-15 Issue:6 Volume:74 Page:1932-1935
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Papadopoulos Chelsea J.¹,Carson Christine F.¹,Chang Barbara J.¹,Riley Thomas V.¹²

Affiliation:

1. Discipline of Microbiology and Immunology, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia

2. Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, Queen Elizabeth II Medical Centre, Nedlands, Western Australia 6009, Australia

Abstract

ABSTRACT Using a series of efflux mutants of Pseudomonas aeruginosa , the MexAB-OprM pump was identified as contributing to this organism's tolerance to the antimicrobial agent tea tree ( Melaleuca alternifolia ) oil and its monoterpene components terpinen-4-ol, 1,8-cineole, and α-terpineol. These data show that a multidrug efflux system of P. aeruginosa can extrude monoterpenes and related alcohols.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.02334-07

Reference32 articles.

1. Banes-Marshall, L., P. Cawley, and C. A. Phillips. 2001. In vitro activity of Melaleuca alternifolia (tea tree) oil against bacterial and Candida spp. isolates from clinical specimens. Br. J. Biomed. Sci.58:139-145.

2. Melaleuca alternifolia (Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties

3. Mechanism of Action of Melaleuca alternifolia (Tea Tree) Oil on Staphylococcus aureus Determined by Time-Kill, Lysis, Leakage, and Salt Tolerance Assays and Electron Microscopy

4. Choi, K. H., A. Kumar, and H. P. Schweizer. 2005. A 10 min method for preparation of highly electrocompetent Pseudomonas aeruginosa cells: application for DNA fragment transfer between chromosomes and plasmid transformation. J. Microbiol. Methods64:391-397.

5. Cross-Resistance between Triclosan and Antibiotics in Pseudomonas aeruginosa Is Mediated by Multidrug Efflux Pumps: Exposure of a Susceptible Mutant Strain to Triclosan Selects nfxB Mutants Overexpressing MexCD-OprJ

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