Antimicrobial susceptibilities of enterococci isolated from hospitalized patients

Author:

Venditti M1,Tarasi A1,Gelfusa V1,Nicastri E1,Penni A1,Martino P1

Affiliation:

1. Servizio Aggregato di Consulenze Infettivologiche, Policlinico Umberto I, Rome, Italy.

Abstract

One hundred and one isolates of Enterococcus species isolated recently from hospitalized patients were evaluated in vitro for antibiotic susceptibility. Teicoplanin and mideplanin were the most active agents, followed by ramoplanin, vancomycin, ciprofloxacin, ampicillin, and imipenem. High-level resistance to gentamicin (MIC > 500 micrograms/ml) and/or streptomycin (MIC > 2,000 micrograms/ml) was found in 60 isolates. High-level resistance to ampicillin (MIC > or = 16 micrograms/ml) was found in 17 isolates. MBC studies revealed that ramoplanin possesses significant bactericidal activity.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference22 articles.

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2. In vitro activities of three semisynthetic amide derivatives of teicoplanin;Biavasco F.;MDL 62208, MDL 62211, and MDL 62873. Antimicrob. Agents Chemother.,1992

3. In vitro activities of ramoplanin and four glycopeptide antibiotics against clinical isolates of Clostridium difficile;Biavasco F.;Antimicrob. Agents Chemother.,1991

4. Emergence and nosocomial transmission of ampicillin-resistant enterococci;Boyce J. M.;Antimicrob. Agents Chemother.,1992

5. Species identification and antibiotic resistance patterns of the enterococci;Brucey E. A.;Eur. J. Clin. Microbiol. Infect. Dis.,1991

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