Safety and Activity of the Immune Modulator HE2000 on the Incidence of Tuberculosis and Other Opportunistic Infections in AIDS Patients-Reference-Cited by-同舟云学术

Safety and Activity of the Immune Modulator HE2000 on the Incidence of Tuberculosis and Other Opportunistic Infections in AIDS Patients

Published:2007-07 Issue:7 Volume:51 Page:2639-2641
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Stickney Dwight R.¹,Noveljic Zoja²,Garsd Armando¹,Destiche Daniel A.¹,Frincke James M.¹

Affiliation:

1. Hollis-Eden Pharmaceuticals, Inc., San Diego, California

2. Karl Bremmer Hospital, Cape Town, Republic of South Africa

Abstract

ABSTRACT Twenty-five AIDS patients were treated with HE2000, a synthetic adrenal hormone. The drug was well tolerated and safe and reduced both the incidence of tuberculosis coinfection by 42.2% ( P < 0.05) and the cumulative incidence of opportunistic infections ( P < 0.05). These results warrant further clinical investigation of HE2000.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01446-06

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