Extracellular Release of Antigenic Proteins by Helicobacter pylori-Reference-Cited by-同舟云学术

Extracellular Release of Antigenic Proteins by Helicobacter pylori

Published:1998-06 Issue:6 Volume:66 Page:2984-2986
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Cao Ping¹,McClain Mark S.¹,Forsyth Mark H.¹,Cover Timothy L.¹²³

Affiliation:

1. Division of Infectious Diseases, Department of Medicine,1 and

2. Department of Microbiology and Immunology,2 Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2605, and

3. Department of Veterans Affairs Medical Center, Nashville, Tennessee 37232-26373

Abstract

ABSTRACT Screening a Helicobacter pylori genomic library with antisera raised against H. pylori broth culture supernatant resulted in the identification of six antigens: urease, HspB, Lpp20, DnaK, MsrA, and a cysteine-rich 28-kDa protein (designated HcpA). H. pylori antigens may be released into the extracellular space by multiple mechanisms, including specific secretion pathways, autolysis, and membrane vesicle formation.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.66.6.2984-2986.1998

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