Tuberculostearic Acid Controls Mycobacterial Membrane Compartmentalization-Reference-Cited by-同舟云学术

Tuberculostearic Acid Controls Mycobacterial Membrane Compartmentalization

Published:2023-04-25 Issue:2 Volume:14 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Prithviraj Malavika¹,Kado Takehiro¹,Mayfield Jacob A.²,Young David C.²,Huang Annie D.²,Motooka Daisuke³,Nakamura Shota³,Siegrist M. Sloan¹⁴^ORCID,Moody D. Branch²,Morita Yasu S.¹⁴^ORCID

Affiliation:

1. Department of Microbiology, University of Massachusetts, Amherst, Massachusetts, USA

2. Division of Rheumatology, Inflammation and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

3. Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan

4. Molecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, Massachusetts, USA

Abstract

As its common name implies, tuberculostearic acid is an abundant and genus-specific branched-chain fatty acid in mycobacterial membranes. This fatty acid, 10-methyl octadecanoic acid, has been an intense focus of research, particularly as a diagnostic marker for tuberculosis.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of General Medical Sciences

Uehara Memorial Foundation

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.03396-22

Reference66 articles.

1. The thick waxy coat of mycobacteria, a protective layer against antibiotics and the host's immune system