Genome-Wide Analysis of Experimentally Evolved Candida auris Reveals Multiple Novel Mechanisms of Multidrug Resistance-Reference-Cited by-同舟云学术

Genome-Wide Analysis of Experimentally Evolved Candida auris Reveals Multiple Novel Mechanisms of Multidrug Resistance

Published:2021-04-27 Issue:2 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Carolus Hans¹²^ORCID,Pierson Siebe²^ORCID,Muñoz José F.³^ORCID,Subotić Ana¹²^ORCID,Cruz Rita B.²,Cuomo Christina A.³^ORCID,Van Dijck Patrick¹²^ORCID

Affiliation:

1. VIB Center for Microbiology, Leuven, Belgium

2. Department of Biology, KU Leuven, Leuven, Belgium

3. Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA

Abstract

Candida auris is a recently discovered human fungal pathogen and has shown an alarming potential for developing multi- and pan-resistance toward all classes of antifungals most commonly used in the clinic. Currently, C. auris has been globally recognized as a nosocomial pathogen of high concern due to this evolutionary potential.

Funder

Fonds Wetenschappelijk Onderzoek

Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases

HHS | NIH | NIAID | Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.03333-20

Reference102 articles.

1. Candida aurissp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital