Cerebral Malaria Is Regulated by Host-Mediated Changes in Plasmodium Gene Expression

Author:

Cimperman Clare K.1,Pena Mirna1,Gokcek Sohret M.234,Theall Brandon P.1,Patel Meha V.1,Sharma Anisha1,Qi ChenFeng1,Sturdevant Daniel5,Miller Louis H.6,Collins Patrick L.34,Pierce Susan K.1,Akkaya Munir234

Affiliation:

1. Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, Rockville, Maryland, USA

2. Division of Rheumatology and Immunology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, Ohio, USA

3. Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, Ohio, USA

4. Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, College of Medicine, The Ohio State University, Columbus, Ohio, USA

5. Research Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana, USA

6. Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Rockville, Maryland, USA

Abstract

Hundreds of thousands of lives are lost each year due to the brain damage caused by malaria disease. The overwhelming majority of these deaths occur in young children living in sub-Saharan Africa.

Funder

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

OSU | College of Medicine Office of Research, Ohio State University

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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