Human Fulminant Gas Gangrene Caused byClostridium chauvoei

Author:

Nagano Noriyuki12,Isomine Shinji3,Kato Haru2,Sasaki Yoshimasa4,Takahashi Motohide2,Sakaida Koji3,Nagano Yukiko2,Arakawa Yoshichika2

Affiliation:

1. Medical Microbiology Laboratory

2. Department of Bacterial Pathogenesis and Infection Control, National Institute of Infectious Diseases

3. Department of Anesthesiology, Funabashi Municipal Medical Center, Chiba

4. Food Safety and Consumer Affairs Bureau, Ministry of Agriculture, Forestry and Fisheries, Tokyo, Japan

Abstract

ABSTRACTThe first human case of fulminant gas gangrene caused byClostridium chauvoei, a pathogen causing ruminant blackleg, was confirmed for a 58-year-old man suffering from diabetes mellitus. The patient developed conspicuous emphysematous gangrene in the right chest wall as well as intravascular gas entrapments and died 2 h after hospital arrival.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference11 articles.

1. Allen, S. D., C. L. Emery, and D. M. Lyerly. 2003. Clostridium, p. 835-856. In P. R. Murray, E. J. Baron, J. H. Jorgensen, M. A. Pfaller, and R. H. Yolken (ed.), Manual of clinical microbiology, 8th ed. ASM Press, Washington, DC.

2. Cato, E. P., W. L. George, and S. M. Finegold. 1986. Genus Clostridium. Prazmowski, 1880, 23AL, p. 1141-1200. In P. H. A. Sneath, N. S. Mair, M. E. Sharpe, and J. G. Holt (ed.), Bergey's manual of systematic bacteriology, vol. 2. The Williams & Wilkins Co., Baltimore, MD.

3. Toxigenic clostridia

4. Kojima, A., I. Uchida, T. Sekizaki, Y. Sasaki, Y. Ogikubo, and Y. Tamura. 2001. Rapid detection and identification of Clostridium chauvoei by PCR based on flagellin gene sequence. Vet. Microbiol.78:363-371.

5. Kornbluth, A. A., J. B. Danzig, and L. H. Bernstein. 1989. Clostridium septicum infection and associated malignancy: report of two cases and review of the literature. Medicine68:30-37.

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