In vitro response of Staphylococcus aureus from cystic fibrosis patients to combinations of linoleic and oleic acids added to nutrient medium

Author:

Campbell I M,Crozier D N,Pawagi A B,Buivids I A

Abstract

The effect of supplementing nutrient substrate with various combinations of concentrations of oleic and linoleic acids on the growth of 11 strains of Staphylococcus aureus was assessed. Whereas increasing the concentration of linoleic acid by itself greatly diminished the growth of all 11 strains, concomitant increases in oleic acid greatly diminished the inhibitory effect of linoleic acid. With oleic acid in the nutrient substrate, most of the strains were induced to produce slime which surrounded the cells. Since the slime incorporated oleic but not linoleic acid, such slime production isolated the cells from direct contact with the growth inhibitor, linoleic acid.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference19 articles.

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5. Campbell I. M. D. N. Crozier J. Silver and I. A. Buivids. 1980. The effect of fatty acids on Staphylococcus aureus in vitro p. 359-364. In J. M. Sturgess (ed.) Perspectives in cystic fibrosis. Proceedings of the Eighth International Congress on Cystic Fibrosis. Canadian Cystic Fibrosis Foundation Toronto.

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