Photochromic Fluorophores Enable Imaging of Lowly Expressed Proteins in the Autofluorescent Fungus Candida albicans-Reference-Cited by-同舟云学术

Photochromic Fluorophores Enable Imaging of Lowly Expressed Proteins in the Autofluorescent Fungus Candida albicans

Published:2021-04-28 Issue:2 Volume:6 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Van Genechten Wouter¹²³^ORCID,Demuyser Liesbeth¹²^ORCID,Duwé Sam³^ORCID,Vandenberg Wim⁴,Van Dijck Patrick¹²^ORCID,Dedecker Peter⁴^ORCID

Affiliation:

1. Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven, Belgium

2. VIB-KU Leuven Center for Microbiology, KU Leuven, Leuven, Belgium

3. Advanced Optical Microscopy Centre, Biomedical Research Institute (BIOMED), Hasselt University, Hasselt, Belgium

4. Lab for Nanobiology, Department of Chemistry, KU Leuven, Leuven, Belgium

Abstract

Understanding the spatial and temporal organization of proteins of interest is key to unraveling cellular processes and identifying novel possible antifungal targets. Only a few therapeutic targets have been discovered in Candida albicans , and resistance mechanisms against these therapeutic agents are rapidly acquired.

Funder

Fonds Wetenschappelijk Onderzoek

European Community ERC Starting Grant

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00146-21

Reference33 articles.

1. Epidemiology of Invasive Candidiasis: a Persistent Public Health Problem

2. Candida albicans and Pseudomonas aeruginosa Interact To Enhance Virulence of Mucosal Infection in Transparent Zebrafish

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5. Function and subcellular localization of Gcn5, a histone acetyltransferase in Candida albicans

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