Detection of Bourbon Virus-Specific Serum Neutralizing Antibodies in Human Serum in Missouri, USA

Author:

Bamunuarachchi Gayan1ORCID,Harastani Houda1,Rothlauf Paul W.23,Dai Ya-nan4,Ellebedy Ali4,Fremont Daved45ORCID,Whelan Sean P. J.2ORCID,Wang David24ORCID,Boon Adrianus C. M.124ORCID

Affiliation:

1. Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA

2. Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA

3. Program in Virology, Harvard Medical School, Boston, Massachusetts, USA

4. Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA

5. Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA

Abstract

Since the discovery of the Bourbon virus (BRBV) in 2014, a total of five human cases have been identified, including two fatal cases. BRBV is thought to be transmitted by the lone star tick, which is prevalent in the eastern, southeastern, and midwestern United States.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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