Exposure to Parasitic Protists and Helminths Changes the Intestinal Community Structure of Bacterial Communities in a Cohort of Mother-Child Binomials from a Semirural Setting in Mexico

Author:

Partida-Rodriguez Oswaldo12ORCID,Nieves-Ramirez Miriam12,Laforest-Lapointe Isabelle345,Brown Eric M.2,Parfrey Laura67,Valadez-Salazar Alicia1,Thorson Lisa2,Morán Patricia1,Gonzalez Enrique1,Rascon Edgar1,Magaña Ulises1,Hernandez Eric1,Rojas-Velázquez Liliana1,Torres Javier8,Arrieta Marie Claire234ORCID,Ximenez Cecilia1,Finlay B. Brett2910ORCID

Affiliation:

1. Laboratorio de Inmunología del Unidad de Medicina Experimental, UNAM, Mexico City, Mexico

2. Michael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada

3. Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada

4. Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada

5. Département de Biologie, Université de Sherbrooke, Sherbrooke, Québec, Canada

6. Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada

7. Department of Botany, University of British Columbia, Vancouver, British Columbia, Canada

8. Unidad de Investigación en Enfermedades Infecciosas, UMAE Pediatria, IMSS, Mexico City, Mexico

9. Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

10. Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada

Abstract

The impact of intestinal eukaryotes on the prokaryotic microbiome composition of asymptomatic carriers has not been extensively explored, especially in infants and mothers with multiple parasitic infections. In this work, we studied the relationship between protist and helminth parasite colonization and the intestinal microbiota structure in an asymptomatic population of mother-child binomials from a semirural community in Mexico.

Funder

PAPIIT UNAM

FIS/IMSS

CONACYT MEXICO

Human Frontier Science Program

Estancias Postdoctorales al extranjero CONACYT Mexico

Gouvernement du Canada | Canadian Institutes of Health Research

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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