Construction of Candida albicans Strains with ATP-Analog-Sensitive Protein Kinase A and Hog1

Abstract

As an opportunistic pathogen in humans, the fungus Candida albicans relies on virulence traits to cause disease. They include the ability to transition from yeast to filamentous morphologies and the ability to grow in diverse environmental stress conditions, including nutrient limitation, as well as osmotic and heat shock.