mSphere of Influence: When a sequencer is more than a sequencer-Reference-Cited by-同舟云学术

mSphere of Influence: When a sequencer is more than a sequencer

Published:2024-09-10 Issue: Volume: Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Billmyre R. Blake¹²³⁴^ORCID

Affiliation:

1. Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, USA

2. Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA

3. Department of Microbiology, Franklin College of Arts and Sciences, University of Georgia, Athens, Georgia, USA

4. Department of Genetics, Franklin College of Arts and Sciences, University of Georgia, Athens, Georgia, USA

Abstract

ABSTRACT Blake Billmyre uses functional genomics to help understand the biology of fungal pathogens, with an emphasis on evolution of virulence relevant traits and drug resistance. In this mSphere of Influence article, he reflects on how two papers (Liachko et al., “High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast,” Genome Research, 2013, and Guo et al., “Integration profiling of gene function with dense maps of transposon integration,” Genetics, 2013) impacted his research trajectory and goals. These articles show the power of creative use of sequencing as a tool to drive understanding of fundamental biology.

Publisher

American Society for Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/msphere.00433-24

Reference15 articles.

1. High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast

2. Rapid mapping of insertional mutations to probe cell wall regulation in Cryptococcus neoformans

3. The Cryptococcus neoformans Alkaline Response Pathway: Identification of a Novel Rim Pathway Activator

4. Identifying Genetic Determinants Needed to Establish a Human Gut Symbiont in Its Habitat

5. Tracking insertion mutants within libraries by deep sequencing and a genome-wide screen for Haemophilus genes required in the lung