Fusarium graminearum Ste3 G-Protein Coupled Receptor: A Mediator of Hyphal Chemotropism and Pathogenesis

Author:

Sharma Tanya12,Sridhar Pooja S.3,Blackman Christopher45,Foote Simon J.6,Allingham John S.3,Subramaniam Rajagopal45,Loewen Michele C.123ORCID

Affiliation:

1. Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada

2. Aquatic and Crop Resources Development Research Center, National Research Council of Canada, Ottawa, Ontario, Canada

3. Department of Biomedical and Molecular Science, Queen’s University, Kingston, Ontario, Canada

4. Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada

5. Agriculture and Agri-Food Canada, Ottawa, Ontario, Canada

6. Human Health Therapeutics Research Center, National Research Council of Canada, Ottawa, Ontario, Canada

Abstract

Fusarium head blight of wheat, caused by the filamentous fungus Fusarium graminearum , leads to devastating global food shortages and economic losses. Fungal hyphal chemotropism has been shown to be a major contributor to host-pathogen interactions. Here, the role of the opposite mating type GPCR, Ste3, is characterized with respect to F. graminearum chemotropism and pathogenicity. These findings contribute to our understanding of the mechanisms underlying fungal chemotropism and pathogenesis.

Funder

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Gouvernement du Canada | National Research Council Canada

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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