Bloom Helicase Along with Recombinase Rad51 Repairs the Mitochondrial Genome of the Malaria Parasite-Reference-Cited by-同舟云学术

Bloom Helicase Along with Recombinase Rad51 Repairs the Mitochondrial Genome of the Malaria Parasite

Published:2021-12-22 Issue:6 Volume:6 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Jha Payal¹,Gahlawat Abhilasha¹,Bhattacharyya Sunanda²,Dey Sandeep³,Kumar Kota Arun³,Bhattacharyya Mrinal Kanti¹^ORCID

Affiliation:

1. Department of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad, India

2. Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Hyderabad, India

3. Department of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, India

Abstract

The impact of malaria on global public health and the world economy continues to surge despite decades of vaccine research and drug development efforts. An alarming rise in resistance toward all the commercially available antimalarial drugs and the lack of an effective malaria vaccine brings us to the urge to identify novel intervention strategies for curbing malaria.

Funder

DST | Science and Engineering Research Board

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00718-21

Reference48 articles.

1. World Health Organization. 2021. Malaria. World Health Organization Geneva Switzerland. https://www.who.int/news-room/fact-sheets/detail/malaria. Accessed 15 April 2021.

2. Fighting drug-resistant Plasmodium falciparum: the challenge of artemisinin resistance

3. Mitochondrial Evolution and Functions in Malaria Parasites

4. Homologies between the contiguous and fragmented rRNAs of the twoPlasmodium falciparum extrachromosomalDNAs are limited to core sequences

5. Complex transcription from the extrachromosomal DNA encoding mitochondrial functions of Plasmodium yoelii

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