Genomics, Transcriptomics, and Metabolomics Reveal That Minimal Modifications in the Host Are Crucial for the Compensatory Evolution of ColE1-Like Plasmids-Reference-Cited by-同舟云学术

Genomics, Transcriptomics, and Metabolomics Reveal That Minimal Modifications in the Host Are Crucial for the Compensatory Evolution of ColE1-Like Plasmids

Published:2022-12-21 Issue:6 Volume:7 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Ares-Arroyo Manuel¹^ORCID,Fernández-García Miguel²,Wedel Emilia¹,Montero Natalia¹,Barbas Coral²^ORCID,Rey-Stolle M. Fernanda¹²,Garcia Antonia²,González-Zorn Bruno¹^ORCID

Affiliation:

1. Antimicrobial Resistance Unit (ARU), Departamento de Sanidad Animal and Centro de Vigilancia Sanitaria Veterinaria (VISAVET), Complutense University of Madrid, Madrid, Spain

2. Center for Metabolomics and Bioanalysis (CEMBIO), Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte, Spain

Abstract

The ability of bacteria to horizontally transfer genetic material has turned antimicrobial resistance into one of the major sanitary crises of the 21st century. Plasmid conjugation is considered the main mechanism responsible for the mobilization of resistance genes, and its understanding is crucial to tackle this crisis.

Funder

Ministerio de Ciencia, Innovación y Universidades

Universidad San Pablo - CEU

European Commission

Universidad Complutense de Madrid

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/msphere.00184-22

Reference70 articles.