A Transducing Bacteriophage Infecting Staphylococcus epidermidis Contributes to the Expansion of a Novel Siphovirus Genus and Implies the Genus Is Inappropriate for Phage Therapy-Reference-Cited by-同舟云学术

A Transducing Bacteriophage Infecting Staphylococcus epidermidis Contributes to the Expansion of a Novel Siphovirus Genus and Implies the Genus Is Inappropriate for Phage Therapy

Published:2023-06-22 Issue:3 Volume:8 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Andrews Taylor¹^ORCID,Hoyer J. Steen²^ORCID,Ficken Karolyn¹,Fey Paul D.³^ORCID,Duffy Siobain²^ORCID,Boyd Jeffrey M.¹^ORCID

Affiliation:

1. Department of Biochemistry and Microbiology, Rutgers University, New Brunswick, New Jersey, USA

2. Department of Ecology, Evolution, and Natural Resources, Rutgers University, New Brunswick, New Jersey, USA

3. University of Nebraska Medical Center, University of Nebraska, Omaha, Nebraska, USA

Abstract

This project describes the discovery of a culturable bacteriophage infecting Staphylococcus epidermidis that is a member of a rapidly growing novel siphovirus genus. A member of this genus was recently characterized and proposed for phage therapy, as there are few phages currently available to treat S. epidermidis infections.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

U.S. Department of Agriculture

National Science Foundation

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/msphere.00524-22

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