CyTOF Profiling of Zika and Dengue Virus-Infected Human Peripheral Blood Mononuclear Cells Identifies Phenotypic Signatures of Monotype Subsets and Upregulation of the Interferon-Inducible Protein CD169-Reference-Cited by-同舟云学术

CyTOF Profiling of Zika and Dengue Virus-Infected Human Peripheral Blood Mononuclear Cells Identifies Phenotypic Signatures of Monotype Subsets and Upregulation of the Interferon-Inducible Protein CD169

Published:2021-06-30 Issue:3 Volume:6 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Fenutria Rafael¹,Maringer Kevin¹,Potla Uma¹,Bernal-Rubio Dabeiba¹,Evans Matthew J.¹,Harris Eva²,Rahman Adeeb H.³⁴,Fernandez-Sesma Ana¹⁵,Ramos Irene¹^ORCID

Affiliation:

1. Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA

2. Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, California, USA

3. Human Immune Monitoring Center, Icahn School of Medicine at Mt. Sinai, New York, New York, USA

4. Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mt. Sinai, New York, New York, USA

5. The Graduate School of Biomedical Sciences at Icahn School of Medicine at Mount Sinai, New York, New York, USA

Abstract

Zika and dengue viruses are emergent arboviruses of great public health impact. Both viruses are responsible for important diseases, yet there is currently no vaccine or specific treatment available.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Wellcome

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00505-21

Reference62 articles.

1. Four human diseases with significant public health impact caused by mosquito-borne flaviviruses: West Nile, Zika, dengue and yellow fever

2. Zika Virus (I). Isolations and serological specificity