A New Contact Killing Toxin Permeabilizes Cells and Belongs to a Broadly Distributed Protein Family-Reference-Cited by-同舟云学术

A New Contact Killing Toxin Permeabilizes Cells and Belongs to a Broadly Distributed Protein Family

Published:2021-08-25 Issue:4 Volume:6 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Crisan Cristian V.¹²³,Chandrashekar Harshini⁴,Everly Catherine¹²³,Steinbach Gabi³⁵,Hill Shannon E.²⁶,Yunker Peter J.³⁵,Lieberman Raquel R.²⁶,Hammer Brian K.¹²³^ORCID

Affiliation:

1. School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA

2. Parker H. Petit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA

3. Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA

4. Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA

5. School of Physics, Georgia Institute of Technology, Atlanta, Georgia, USA

6. School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, USA

Abstract

Bacteria live in polymicrobial communities where competition for resources and space is essential for survival. Proteobacteria use the T6SS to eliminate neighboring cells and cause disease.

Funder

United States-Israel Binational Science Foundation

Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften

National Science Foundation

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00318-21

Reference94 articles.

1. Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system