Identification of an α-(1 6)-Mannosyltransferase Contributing To Biosynthesis of the Fungal-Type Galactomannan α-Core-Mannan Structure in Aspergillus fumigatus

Author:

Kadooka Chihiro1,Hira Daisuke1,Tanaka Yutaka2,Miyazawa Ken3ORCID,Bise Masaaki1,Takatsuka Shogo3,Oka Takuji1ORCID

Affiliation:

1. Department of Biotechnology and Life Sciences, Sojo University, Kumamoto, Japan

2. Division of Infection and Host Defense, Tohoku Medical and Pharmaceutical University, Sendai, Japan

3. Department of Fungal Infection, National Institute of Infectious Diseases, Tokyo, Japan

Abstract

Fungal-type galactomannan is a polysaccharide incorporated into the cell wall of filamentous fungi belonging to the subphylum Pezizomycotina. Biosynthetic enzymes of fungal-type galactomannan are potential targets for antifungal drugs and agrochemicals.

Funder

MEXT | Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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