The Multidrug Efflux Regulator AcrR of Escherichia coli Responds to Exogenous and Endogenous Ligands To Regulate Efflux and Detoxification-Reference-Cited by-同舟云学术

The Multidrug Efflux Regulator AcrR of Escherichia coli Responds to Exogenous and Endogenous Ligands To Regulate Efflux and Detoxification

Published:2022-12-21 Issue:6 Volume:7 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Harmon Dana E.¹,Ruiz Cristian¹^ORCID

Affiliation:

1. Department of Biology, California State University Northridge, Northridge, California, USA

Abstract

Multidrug efflux pumps can remove antibiotics and other toxic molecules from cells and are major contributors to antibiotic resistance and bacterial physiology. Therefore, it is essential to better understand their function and regulation.

Funder

National Science Foundation

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/msphere.00474-22

Reference40 articles.

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2. Centers for Disease Control and Prevention. 2019. Antibiotic resistance threats in the United States 2019. https://stacks.cdc.gov/view/cdc/82532. Accessed 15 September 2022.

3. The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria

4. Efflux-Mediated Antimicrobial Resistance in Bacteria

5. Multidrug efflux pumps: structure, function and regulation

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