Molecular and Epidemiological Characteristics of Carbapenemase-Producing Klebsiella pneumoniae Clinical Isolates in Japan-Reference-Cited by-同舟云学术

Molecular and Epidemiological Characteristics of Carbapenemase-Producing Klebsiella pneumoniae Clinical Isolates in Japan

Published:2020-10-28 Issue:5 Volume:5 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Yonekawa Shinsuke¹,Mizuno Tomoki²,Nakano Ryuichi²^ORCID,Nakano Akiyo²,Suzuki Yuki²,Asada Tomoko²,Ishii Ayako²,Kakuta Naoki²,Tsubaki Kosuke²,Mizuno Sayaka²,Ogawa Miho³,Yano Hisakazu²,Kasahara Kei¹,Mikasa Keiichi¹

Affiliation:

1. Center for Infectious Diseases, Nara Medical University, Kashihara, Nara, Japan

2. Department of Microbiology and Infectious Diseases, Nara Medical University, Kashihara, Nara, Japan

3. Department of Bacteriology, BML Inc., Kawagoe, Saitama, Japan

Abstract

Carbapenems serve as a last resort for the clinical treatment of multidrug-resistant infections. Therefore, the rapid spread of carbapenemase-producing strains represents a serious public health threat, further limiting antibiotic choices. The current findings of hypervirulent carbapenemase-producing Klebsiella pneumoniae clinical isolates in Japan demonstrate the potential broad spread and transfer of these genes, necessitating close surveillance.

Funder

MEXT | Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00490-20

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