Toxoplasma gondii AP2XII-2 Contributes to Transcriptional Repression for Sexual Commitment

Author:

Srivastava Sandeep1ORCID,Holmes Michael J.1ORCID,White Michael W.2,Sullivan William J.13ORCID

Affiliation:

1. Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA

2. Department of Global Health, University of South Florida, Tampa, Florida, USA

3. Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA

Abstract

Toxoplasma gondii is a parasite that undergoes its sexual stage exclusively in feline intestines, making cats a major source of transmission. A better understanding of the proteins controlling the parasite’s life cycle stage transitions is needed for the development of new therapies aimed at treating toxoplasmosis and the transmission of the infection.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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