High-Surety Isothermal Amplification and Detection of SARS-CoV-2-Reference-Cited by-同舟云学术

High-Surety Isothermal Amplification and Detection of SARS-CoV-2

Published:2021-05-19 Issue: Volume: Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Bhadra Sanchita¹²^ORCID,Riedel Timothy E.³,Lakhotia Simren³,Tran Nicholas D.³,Ellington Andrew D.¹²^ORCID

Affiliation:

1. Department of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, Texas, USA

2. Center for Systems and Synthetic Biology, The University of Texas at Austin, Austin, Texas, USA

3. Freshman Research Initiative, DIY Diagnostics Stream, The University of Texas at Austin, Austin, Texas, USA

Abstract

One of the key approaches to treatment and control of infectious diseases, such as COVID-19, is accurate and rapid diagnostics that is widely deployable in a timely and scalable manner. To achieve this, it is essential to go beyond the traditional gold standard of quantitative PCR (qPCR) that is often faced with difficulties in scaling due to the complexity of infrastructure and human resource requirements.

Funder

HHS | National Institutes of Health

National Science Foundation

Welch Foundation

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00911-20

Reference40 articles.

1. Loop-mediated isothermal amplification of DNA