Association between Pregestational Vaginal Dysbiosis and Incident Hypertensive Disorders of Pregnancy Risk: a Nested Case-Control Study

Author:

Li Xiao12ORCID,Tian Zhaomei12,Cui Ran12,Lv Jiale12,Yang Xin123,Qin Lang12,Liu Zheng12,Zhang Changlong12,Jin Congcong124,Xu Yanqi125,Chen Zi-Jiang12678,Zhao Han129,Zhao Shigang12ORCID

Affiliation:

1. Center for Reproductive Medicine, Shandong University, Jinan, Shandong, China

2. Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, Shandong, China

3. Reproductive Medicine Center of Zibo Maternal and Child Health Care Hospital, Zibo, Shandong, China

4. Reproductive Medicine Center of The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

5. Linyi People's Hospital, Linyi, Shandong, China

6. Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China

7. Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China

8. Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences, China

9. Shandong Key Laboratory of Reproductive Medicine, Shandong First Medical University, Jinan, Shandong, China

Abstract

The etiology of HDP remains unclear to date. Effective methods for the individualized prediction and prevention are lacking.

Funder

Basic Science Center Program of Natural Science Foundation of China

Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences

Shandong Provincial Key Research and Development Program

Innovative Research Team of High-level Local Universities in Shanghai

Fundamental Research Funds of Shandong University

CAMS Innovation Fund for Medical Sciences

National Key Research and Development Program of China

National Natural Science Foundation of China

Taishan Scholar Project of Shandong Province

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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