A Novel Trimethoprim Resistance Gene, dfrA36 , Characterized from Escherichia coli from Calves-Reference-Cited by-同舟云学术

A Novel Trimethoprim Resistance Gene, dfrA36 , Characterized from Escherichia coli from Calves

Published:2019-06-26 Issue:3 Volume:4 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Wüthrich Dominik¹,Brilhante Michael¹²,Hausherr Anna¹,Becker Jens²³,Meylan Mireille³,Perreten Vincent¹^ORCID

Affiliation:

1. Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

2. Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland

3. Clinic for Ruminants, Vetsuisse Faculty, University of Bern, Bern, Switzerland

Abstract

The presence of dfrA36 associated with IS CR2 in Escherichia coli from animals, as well as its presence in other E. coli strains from different sources and countries and in Acinetobacter , highlights the global spread of this gene and its potential for further dissemination. The genetic link of IS CR2 - dfrA36 with other antibiotic and disinfectant resistance genes showed that multidrug-resistant E. coli may be selected and maintained by the use of either one of several antimicrobials.

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00255-19

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