Enterococcal PrgU Provides Additional Regulation of Pheromone-Inducible Conjugative Plasmids-Reference-Cited by-同舟云学术

Enterococcal PrgU Provides Additional Regulation of Pheromone-Inducible Conjugative Plasmids

Published:2021-06-09 Issue: Volume: Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Lassinantti Lena¹^ORCID,Camacho Martha I.²,Erickson Rebecca J. B.³,Willett Julia L. E.³,De Lay Nicholas R.²,ter Beek Josy¹^ORCID,Dunny Gary M.³,Christie Peter J.²,Berntsson Ronnie P.-A.¹⁴^ORCID

Affiliation:

1. Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden

2. Department of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA

3. Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA

4. Wallenberg Centre for Molecular Medicine, Umeå University, Umeå, Sweden

Abstract

Bacteria utilize type 4 secretion systems (T4SS) to efficiently transfer DNA between donor and recipient cells, thereby spreading genes encoding antibiotic resistance as well as various virulence factors. Regulation of expression of the T4SS proteins and surface adhesins in Gram-positive bacteria is crucial, as some of these are highly toxic to the cell.

Funder

Vetenskapsrådet

Kempestiftelserna

Carl Tryggers Stiftelse för Vetenskaplig Forskning

National Institutes of Health

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00264-21