Metagenomic Analysis of the Abundance and Composition of Antibiotic Resistance Genes in Hospital Wastewater in Benin, Burkina Faso, and Finland

Author:

Markkanen Melina A.12ORCID,Haukka Kaisa13,Pärnänen Katariina M. M.1ORCID,Dougnon Victorien Tamegnon4,Bonkoungou Isidore Juste O.5,Garba Zakaria6,Tinto Halidou6,Sarekoski Anniina1,Karkman Antti12ORCID,Kantele Anu273,Virta Marko P. J.12ORCID

Affiliation:

1. Department of Microbiology, University of Helsinki, Helsinki, Finland

2. Multidisciplinary Center of Excellence in Antimicrobial Resistance Research, University of Helsinki, Helsinki, Finland

3. Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland

4. Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, Benin

5. Department of Biochemistry and Microbiology, University Joseph Ki-Zerbo, Ouagadougou, Burkina Faso

6. Clinical Research Unit Nanoro, Institute for Research in Health Sciences, National Center for Scientific and Technological Research, Ouagadougou, Burkina Faso

7. Meilahti Vaccine Research Center MeVac, Department of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

Abstract

The global emergence and increased spread of antibiotic resistance threaten the effectiveness of antibiotics and, thus, the health of the entire population. Therefore, understanding the resistomes in different geographical locations is crucial in the global fight against the antibiotic resistance crisis.

Funder

University of Helsinki HiLife Grand Challenges

Academy of Finland

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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