Multidimensional Clinical Surveillance of Pseudomonas aeruginosa Reveals Complex Relationships between Isolate Source, Morphology, and Antimicrobial Resistance-Reference-Cited by-同舟云学术

Multidimensional Clinical Surveillance of Pseudomonas aeruginosa Reveals Complex Relationships between Isolate Source, Morphology, and Antimicrobial Resistance

Published:2021-08-25 Issue:4 Volume:6 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Dunphy Laura J.¹^ORCID,Kolling Glynis L.¹²,Jenior Matthew L.¹,Carroll Joanne³,Attai April E.³,Farnoud Farzad⁴,Mathers Amy J.²³,Hughes Molly A.²,Papin Jason A.¹²⁵^ORCID

Affiliation:

1. Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA

2. Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA

3. Clinical Microbiology Laboratory, Department of Pathology, University of Virginia Health System, Charlottesville, Virginia, USA

4. Department of Electrical and Computer Engineering, University of Virginia, Charlottesville, Virginia, USA

5. Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA

Abstract

P. aeruginosa is a leading cause of nosocomial infection and infection in patients with cystic fibrosis. While P. aeruginosa infection and treatment can be complicated by a variety of antimicrobial resistance and virulence mechanisms, pathogen virulence is rarely recorded in a clinical setting.

Funder

University of Virginia School of Medicine Wagner Fellowship

University of Virginia Global Infectious Diseases Institute

University of Virginia 3Cavaliers

National Science Foundation

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00393-21

Reference64 articles.

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3. Pseudomonas aeruginosa – a phenomenon of bacterial resistance

4. Lung Infections Associated with Cystic Fibrosis

5. Cystic Fibrosis Foundation. 2019. Cystic Fibrosis Foundation patient registry 2018 annual data report. Cystic Fibrosis Foundation Bethesda MD. https://www.cff.org/Research/Researcher-Resources/Patient-Registry/2018-Patient-Registry-Annual-Data-Report.pdf.

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