Transcriptional Profiling of the Candida auris Response to Exogenous Farnesol Exposure-Reference-Cited by-同舟云学术

Transcriptional Profiling of the Candida auris Response to Exogenous Farnesol Exposure

Published:2021-10-27 Issue:5 Volume:6 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Jakab Ágnes¹^ORCID,Balla Noémi²³,Ragyák Ágota¹⁴,Nagy Fruzsina²,Kovács Fruzsina²³,Sajtos Zsófi⁴,Tóth Zoltán²,Borman Andrew M.⁵⁶^ORCID,Pócsi István¹,Baranyai Edina⁴,Majoros László²,Kovács Renátó²⁷^ORCID

Affiliation:

1. Department of Molecular Biotechnology and Microbiology, Institute of Biotechnology, Faculty of Science and Technology, University of Debrecen, Debrecen, Hungary

2. Department of Medical Microbiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

3. Doctoral School of Pharmaceutical Sciences, University of Debrecen, Debrecen, Hungary

4. Department of Inorganic and Analytical Chemistry, Agilent Atomic Spectroscopy Partner Laboratory, University of Debrecen, Debrecen, Hungary

5. UK National Mycology Reference Laboratory, Public Health England, Science Quarter, Southmead Hospital, Bristol, United Kingdom

6. Medical Research Council Centre for Medical Mycology (MRC CMM), University of Exeter, Exeter, United Kingdom

7. Faculty of Pharmacy, University of Debrecen, Debrecen, Hungary

Abstract

Candida auris is a dangerous fungal pathogen that causes outbreaks in health care facilities, with infections associated with a high mortality rate. As conventional antifungal drugs have limited effects against the majority of clinical isolates, new and innovative therapies are urgently needed.

Funder

Innovációs és Technológiai Minisztérium

Hungarian National Research, Development and Innovation Office

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00710-21

Reference48 articles.

1. Multidrug-Resistant Candida auris Infections in Critically Ill Coronavirus Disease Patients, India, April–July 2020

2. Spread of Carbapenem-Resistant Gram-Negatives and Candida auris during the COVID-19 Pandemic in Critically Ill Patients: One Step Back in Antimicrobial Stewardship?