The Colorectal Cancer Gut Environment Regulates Activity of the Microbiome and Promotes the Multidrug Resistant Phenotype of ESKAPE and Other Pathogens

Author:

Lamaudière Matthew T. F.1,Arasaradnam Ramesh234,Weedall Gareth D.5,Morozov Igor Y.1ORCID

Affiliation:

1. Centre for Sports, Exercise and Life Sciences, Coventry University, Coventry, United Kingdom

2. Divison of Biomedical Sciences, Warwick Medical School, University of Warwick, Warwick, United Kingdom

3. Department of Gastroenterology, University Hospitals of Coventry and Warwickshire, NHS trust, Coventry, United Kingdom

4. University of Leicester, Leicester, United Kingdom

5. School of Biological and Environmental Sciences, Liverpool John Moors University, Liverpool, United Kingdom

Abstract

The human gut microbiota in colorectal cancer patients have a distinct population compared to heathy counterparts. However, the activity (gene expression) of this community has not been investigated.

Funder

Coventry University

University Hospitals Coventry and Warwickshire NHS Trust

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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