Glucose-6-Phosphate Acts as an Extracellular Signal of SagS To Modulate Pseudomonas aeruginosa c-di-GMP Levels, Attachment, and Biofilm Formation-Reference-Cited by-同舟云学术

Glucose-6-Phosphate Acts as an Extracellular Signal of SagS To Modulate Pseudomonas aeruginosa c-di-GMP Levels, Attachment, and Biofilm Formation

Published:2021-02-24 Issue:1 Volume:6 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Park Soyoung¹²,Dingemans Jozef¹²^ORCID,Gowett Madison¹²,Sauer Karin¹²^ORCID

Affiliation:

1. Department of Biological Sciences, Binghamton University, Binghamton, New York, USA

2. Binghamton Biofilm Research Center, Binghamton University, Binghamton, New York, USA

Abstract

Pathogens sense and respond to signals and cues present in their environment, including host-derived small molecules to modulate the expression of their virulence repertoire. Here, we demonstrate that the opportunistic pathogen Pseudomonas aeruginosa responds to glucose-6-phosphate.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.01231-20

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