Characterization of a 2016-2017 Human Seasonal H3 Influenza A Virus Spillover Now Endemic to U.S. Swine-Reference-Cited by-同舟云学术

Characterization of a 2016-2017 Human Seasonal H3 Influenza A Virus Spillover Now Endemic to U.S. Swine

Published:2022-02-23 Issue:1 Volume:7 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Sharma Aditi¹,Zeller Michael A.¹^ORCID,Souza Carine K.²,Anderson Tavis K.²^ORCID,Vincent Amy L.²^ORCID,Harmon Karen¹,Li Ganwu¹,Zhang Jianqiang¹^ORCID,Gauger Phillip C.¹^ORCID

Affiliation:

1. Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA

2. Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, Iowa, USA

Abstract

H3.2010.2 is a new phylogenetic clade of H3N2 circulating in swine that became established after the spillover of a human seasonal H3N2 from the 2016–2017 influenza season. The novel H3.2010.2 transmitted and adapted to the swine host and demonstrated reassortment with internal genes from strains endemic to pigs, but it maintained human-like HA and NA.

Funder

DOD | Defense Advanced Research Projects Agency

DOE | Oak Ridge Institute for Science and Education

HHS | NIH | National Institute of Allergy and Infectious Diseases

USDA | Agricultural Research Service

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/msphere.00809-21

Reference54 articles.