Replication Kinetics, Cell Tropism, and Associated Immune Responses in SARS-CoV-2- and H5N1 Virus-Infected Human Induced Pluripotent Stem Cell-Derived Neural Models-Reference-Cited by-同舟云学术

Replication Kinetics, Cell Tropism, and Associated Immune Responses in SARS-CoV-2- and H5N1 Virus-Infected Human Induced Pluripotent Stem Cell-Derived Neural Models

Published:2021-06-30 Issue:3 Volume:6 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Bauer Lisa¹^ORCID,Lendemeijer Bas²^ORCID,Leijten Lonneke¹,Embregts Carmen W. E.¹,Rockx Barry¹,Kushner Steven A.²^ORCID,de Vrij Femke M. S.²^ORCID,van Riel Debby¹^ORCID

Affiliation:

1. Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands

2. Department of Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands

Abstract

Infections with the recently emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are often associated with neurological complications. Evidence suggests that SARS-CoV-2 enters the brain via the olfactory nerve; however, SARS-CoV-2 is only rarely detected in the central nervous system of COVID-19 patients.

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

EUR Fellowship

Erasmus MC HUman Disease Model Award

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00270-21

Reference57 articles.

1. Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study